Bioinformatics, Genomics, Proteomics


Computational Biology

John D. Furber

Master of Science, Biological Sciences, University of California, Irvine.
Bachelor of Arts, Physics and Mathematics, University of California, Santa Cruz.

[John D. Furber home page]

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Bioinformatics and Genomics

Bioinformatics is the scientific discipline of discovering biological functions through analysis of molecular sequence information from DNA, RNA, or proteins. Tasks include:Bioinformatics is sometimes called "Functional Genomics." Genomics is study of entire genomes, the complete set of DNA sequences of cells and organisms. The human genome consists of 3 billion pairs of DNA nucleotides (base-pairs) which encode an estimated 50,000 to 120,000 genes. Celera Genomics has a tutorial called What's a Genome?

Proteomics is the study of all of the proteins in a cell, tissue, or organism, rather than studying them one at a time. The interactions of the proteins are very important. Current proteomics techniques involve electrophoretic separation on a 2-dimensional polyacrylamide gel. Other analytical techniques under development make use of antibody affinities or physical and chemical properties of protein sequences. Bioinformatics also uses the gene sequences to predict what proteins should be present.

Genomics tasks include:

These problems can be highly complex, and some of the databases are very large, requiring the use of computers with sophistocated algorithms. Several of these tools and databases are publicly available on the WWW.

Protein Families, Motifs, and Domains

Computational Biology

Bioinformatics Companies

Related Topics

Contact information:

John D. Furber
E-mail: johnfurber at
Telephone: 1-352-271-8711
Gainesville, Florida.
[John D. Furber home page]
© 2000 - 2004 by John D. Furber. All rights Reserved.